SCFD1 and amyotrophic lateral sclerosis: Using the ROSMAP dataset, MR analysis of brain pQTL and ALS GWAS verified that SARM1 (OR = 0.33, p = 2.10 × 10−7), SCFD1 (OR = 4.54, p = 3.72 × 10−13), and DHRS11 (OR = 0.61, p = 7.40 × 10−5) provided evidence of a causal association with ALS.