MAPT and Creutzfeldt Jacob disease: He termed these proteins prions, for proteinaceous infectious particles (151), and in the years since this discovery numerous other proteins, with tau among them, have been shown to behave in a similar fashion to CJD prions at the cellular and biochemical level (128, 135, 152), with the notable exception being that no other disease-related amyloid protein has been shown to be infectious or transmissible between hosts as in CJD (153).