Significantly higher levels of anti-MBP and anti-MOG antibodies were found in the EVs from patients with MS (16.57 ± 5.73 ng/mL and 14.48 ± 12.37 ng/mL, respectively) compared with that of the healthy controls (1.85 ± 1.15 ng/mL and 0.16 ± 0.37 ng/mL) (p=0.001 and p=0.001, respectively) (Figure 4A). The gene discussed is MBP; the disease is myeloid sarcoma.