MBP and myeloid sarcoma: ROC curve analysis indicated a cut-off of 3.95 ng/mL (sensitivity: 95.2%, specificity: 88.2%) of B-cell-derived anti-MBP antibodies (area under the curve = 0.92), and a cut-off of 4.69 ng/mL (sensitivity: 81.5%, specificity: 79.7%) of B-cell-derived anti-MOG antibodies (area under the curve = 0.82) for distinguishing MS occurrence (Figure 4B).