Similar levels of anti-MBP autoantibodies were found in total EVs in the 39 healthy controls (1.94 ± 0.97 ng/mL) and in the 23 white matter lesion control group (1.69 ± 0.7 ng/mL) compared with the 136 patients with MS (2.26 ± 1.32 ng/mL). The gene discussed is MBP; the disease is myeloid sarcoma.