In regard to the HLA-DQB1 locus, which has been studied in the Kuwaiti population (32), we identified the same allele, DQB1*02:01:01 [OR (95% CI) = 3.6 (2.3–5.66), Pc = 2.2 x 10-8], to be strongly associated with the risk of developing T1D; this has also been reported in the Arab (27–29, 41–43), Korean (40), and Caucasian populations, and has been known to confer risk of T1D (7, 9). This evidence concerns the gene HLA-DQB1 and type 1 diabetes mellitus.