HLA-DQA1 and type 1 diabetes mellitus: Additionally, several amino acid changes that were significantly associated with T1D identified on the HLA-DQA1 gene have not been reported before, such as DQα1-11, DQα1-18, DQα1-26, DQα1-41, DQα1-45, DQα1-47, DQα1-48, DQα1-50, DQα1-52, DQα1-53, DQα1-56, DQα1-61, DQα1-64, DQα1-76, DQα1-80, DQα1-130, DQα1-175, DQα1-187, and DQα1-218.