The strongest association that conferred risk of T1D on the HLA-DRß1 positions were DRß1-Tyr-21, DRß1-Leu-67, DRß1-Lys-71, and DRß1-Arg-74 (Pc = 6.4 x 10-6, Pc = 3.6 x 10-5, Pc = 0.0001, and Pc = 0.0001, respectively). Here, DR1 is linked to type 1 diabetes mellitus.