Furthermore, core TFs that mediate crosstalk between inflammation and cell differentiation had expression that was correlated with groups with p-PB (adults with COVID-19, children with dengue): FOS and KLF2 had increased expression in groups with p-PBs, as did the TFs ZEB2, which plays a role in B cell maturity and EMT, and TFEB, involved in autophagy (44). The gene discussed is FOS; the disease is COVID-19.