NLRP3 and experimental autoimmune encephalomyelitis: Moreover, in our another study, we found that 1,2,4-Trimethoxybenzene (1,2,4-TTB) could inhibit NLRP3 inflammasome activation to reduce clinical symptoms and inflammation in experimental autoimmune encephalomyelitis (EAE) (28), suggesting that 1,2,4-TTB might be used in the treatment of inflammatory diseases driven by NLRP3 inflammasome.