In our comparison of macrophage densities and patient survival, higher densities (median density used as a cuff off) of CD68+MRP8-14+CD86neg M1 macrophages in the tumor center was associated with a poorer overall survival (median 2.34 years) compared to the lower densities of this subtype (median 6.41 years) in univariate analysis (Figure 6). The gene discussed is CD68; the disease is neoplasm.