ACS: acute coronary syndrome, CVD: cardiovascular disease, HF: heart failure, ECM: extracellular matrix, IL: interleukin, NLRP3: nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3, MI: myocardial infarction, SICM: sepsis-induced cardiomyopathy. This evidence concerns the gene NLRP3 and cardiovascular disorder.