Several treatment modalities, such as the debridement, antibiotics, and implant retention (DAIR) procedure, one or two-stage revision arthroplasty, arthrodesis, and amputation, have been proposed as treatment options for periprosthetic joint infection (PJI); however, the two-stage revision surgery appears to be the most commonly preferred procedure [1].Along with clinical findings, C-reactive protein (CRP) is one of the most sensitive parameters and is widely used in everyday clinical practice, especially for evaluating the effectiveness of medical treatment over time. The gene discussed is CRP; the disease is juvenile polyposis syndrome.