ETNPPL and cancer: Deng et al. (2020) found that ETNPPL can regulate phosphatidylinositol and phosphatidylserine metabolism in cancer tissues, and knockdown of ETNPPL expression can induce autophagy in colorectal cancer cells. Ding et al. (2016) first found that ETNPPL expression is decreased in HCC and its low expression suggests poor prognosis.