Bioinformatics analysis suggested that TARS1 overexpression was associated with T stage (T1 < T2), ER(Estrogen receptor) status (positive < negative), PR (Progesterone receptors) status (positive < negative), HER-2 (Human epidermal growth factor receptor 2) status (positive > negative) in breast cancer patients, PAM50 (LumA < LumB, HER-2, Basal) and Histological type (infiltrating ductal carcinoma > infiltrating lobular carcinoma), but not N stage, M stage and Pathological stage was not relevant (Figure 3, Supplementary Table 1). This evidence concerns the gene ESR1 and breast cancer.