When splenectomy, which was only performed in 2 patients, was omitted from the model, post-transplant G-CSF (p=0.002, HR: 0.301) and grade 3 vs grade 1 BM fibrosis (p=0.026, HR: 0.179) maintained significant effects along with splenomegaly (p=0.021, HR: 0.94, Supplementary Tables 3, 4) in line with similar cohorts (11, 32). This evidence concerns the gene CSF3 and Splenomegaly.