Correspondingly, EPHB6 expression negatively correlated with most steps engaged in cancer immunity cycle, including the step 1 of cancer cell antigen release and step 4 of basophil, CD8+ T cell, dendritic cell, eosinophil, macrophage, MDSC, neutrophil, NK cell, Th1 cell, Th17 cell, and Th22 cell recruiting (p<0.05; Figure 3B). Here, EPHB6 is linked to cancer.