In addition, Colo 320 CD133–cells were affected relatively more than CD133+ cells from B-CDs.While B-CDs did not affect the control cells, the colon cancer stemcells (Colo 320 CD133+) were affected in a time-dependent manner.Therefore, the use of the synthesized B-CD product may be an alternativemethod for controlling or eliminating cancer stem cells in the tumortissue. The gene discussed is PROM1; the disease is malignant colon neoplasm.