HAS1 and central nervous system cancer: HAS1 was observed to be significantly positively correlated with TMB in three types of tumors, namely SARC, THYM, and ACC; and significantly negatively correlated with TMB in eight types of tumors, namely GBM, glioma (GBMLGG), LGG, ESCA, stomach and esophageal carcinoma (STES), STAD, LIHC, PAAD.