MASP1 and lobular neoplasia: As shown in Fig. 1A, significantly lower levels of MASP-1 were observed in P-LN patients (median 854.28 ng/mL; IQR 330.60, 2013.23 ng/mL) than in NHCs (median 3112.82 ng/mL; IQR 2640.51, 5185.97 ng/mL).