The lower levels of MASP-2 were significantly seen in P-LN patients (median 127.20 ng/mL; IQR 112.65, 138.35 ng/mL) than in NHCs (median 155.30 ng/mL; IQR 152.35, 167.10 ng/mL). Here, MASP2 is linked to lobular neoplasia.