CORIN and cardiac hypertrophy: In the TAC-operated Corin KO mice that received sCorin injection, cardiac hypertrophy was markedly reduced, as indicated by smaller hearts (Figures 6A,B) and reduced ratios of HW to BW (Figure 6C) or TL (Figure 6D) (Supplementary Table S4), compared to those in the TAC-operated Corin KO mice receiving the vehicle.