Both types of receptors recognize PAMPs or DAMPs via diverse extracellular domains and require assistance of co-receptors for signal transduction, resulting in calcium (Ca2+) influx, reactive oxygen species burst, activation of calcium-dependent kinases (CDPKs) and mitogen-activated protein kinases (MAPKs), hormone signaling, and changes in gene expression, all directed at confinement of the infection (Tang et al., 2017; Zhang and Zhang, 2022). This evidence concerns the gene WNK2 and infection.