NPPB and hydrops fetalis: Primary end points were (1) Mean NT-proBNP and (2) a composite of the proportion of patients that achieved a meaningful improvement in health status (≥5-point increase in KCCQ-OS) or (≥20% decrease in NT-proBNP).Key secondary end points included proportion of patients with meaningful change in KCCQ, and NT-proBNP at each time point, mean BNP and proportion of patients with meaningful change in BNP, functional status based on 6-minute walk test, change in weight, systolic BP and HbA1c.Exploratory end points included a composite of hospitalization for HF or urgent HF visits.