As a result, circ_0067934 elevation inhibits the regulatory effect of miRNA-1182 and increases KLF8 levels, leading to the upregulation of EMT and the Wnt/β-catenin pathway, as well as tumor progression in NSCLC patients (Zhao et al., 2020[143]). This evidence concerns the gene KLF8 and non-small cell lung carcinoma.