Even though phosphate homeostasis is finely mediated by three main regulators such as vitamin D, parathyroid hormone (PTH), and fibroblast growth factor 23 (FGF-23), hypophosphatemia (<0.80 mmol/L or <2.48 mg/dL) can occur owing to decreased intestinal absorption, internal redistribution, and increased renal loss (5). This evidence concerns the gene FGF23 and hypophosphatemia.