Anti-TPO Ab-positive patients were about threefold higher among patients with PCOS versus patients without PCOS (OR 3.32, 95% CI 1.25 to 8.87) and anti-TG Ab-positive patients were about twofold higher among patients with PCOS versus patients without PCOS (OR 1.93, 95% CI 1.23 - 3.02) (14). The gene discussed is TPO; the disease is polycystic ovary syndrome.