GLUL and hepatocellular carcinoma: Glypican-3, heat shock protein 70, and GS are utilized to distinguish a <2 cm hepatocellular lesion without classic radiological characters of HCC with cirrhosis by immunochemistry (IHC) or designed RNA probes (Tremosini et al., 2012; Di Tommaso and Roncalli, 2017; Bakheet et al., 2020).