SOCS1 and renal fibrosis: One study showed that miR-150 antagonist induced an increase in markers of renal fibrosis (e.g., α-SMA, FN, and COL-1) in ICR mice, and this inducement was associated with the regulation of the SOCS1/JAK/STAT pathway, which is downstream of miR-150 (Luan et al., 2020).