In this study, Folcher et al (2023) observed an upregulation of NALCN in prostate cancer and associated metastatic tumor tissues compared with normal prostate tissues, and this correlated with the expression of Src, a tyrosine kinase that stimulates cancer invasion by interacting with matrix metalloproteinases and several proteins associated with cancer cell aggressive behavior. The gene discussed is NALCN; the disease is Familial prostate cancer.