TCAF2 and neoplasm: The tumor vessels tended to destabilize with increased MVD and dilated vascular size (Figure S29A, Supporting Information) and decreased pericyte coverage (Figure S29B, Supporting Information) and an incomplete basement membrane (Figure S29C, Supporting Information) in tumor metastasis, which may be resulted from the detachment of pericytes due to pericyte‐fibroblast transition.[8] However, TCAF2 in TPCs had negligible effects on the morphology and function of tumor vessels, indicating that TCAF2 could serve as an early diagnostic marker for hematogenous tumor metastasis.