Among these putative targets, some have been validated as direct targets of miR-203 in diverse cancers, such as BIRC5 in prostate and ovarian cancer cells39, 40, BANF1 in cervical cancer cells41, TYMS in colorectal cancer cells42 and SRC in lung and prostate cancer cells43, 44. The gene discussed is TYMS; the disease is Familial prostate cancer.