In PCa, Darnel et al. analyzed the tissue sample of 196 men who underwent radical prostatectomy and found epithelial FSCN1 expression to be higher in localized and castration resistant PCa compared to benign prostate tissue while no correlation was found between FSCN1 epithelial expression and surgical margins, stage and Gleason score [25]. The gene discussed is FSCN1; the disease is posterior cortical atrophy.