CD8A and neoplasm: In detail, the population of CD8+ T cells in ADPAH@AOT-Bro/NIR-II group reached the highest expression levels, which was 2.0- and 1.5-fold higher than ADPAH@AOT or ADPAH@AOT-Bro group in the primary tumor, and 2.1- and 1.7-fold higher in the distant tumor, respectively (Supplementary Figs. 26 and 27).