Although a high prevalence of germline SAMD9/9L or GATA2 mutations were reported in pediatric MDS with -7 [16], in our cohort of adult patients, SAMD9L germline mutations were identified in only 2 cases while no SAMD9 nor GATA2 germline alterations were found. The gene discussed is GATA2; the disease is myelodysplastic syndrome.