GALNT7 and neoplasm: Thus, we hypothesized that GALNT7 could be a bona fide transcriptional target of SPDEF. To confirm that GALNT7 is indeed the downstream target that mediating the tumor-promoting and stemness maintenance property of SPDEF, the expression of GALNT7 was restored in SPDEF stably inhibited sh-SPDEF cells by overexpressing of GALNT7 (Fig. 4E, F).