PTBP3 and hepatocellular carcinoma: As reflected by the results of western blot analysis, the p-PI3K, p-AKT and PTBP3 expression as well as p-AKT/AKT ratio was decreased in HepG2 and Huh7 cells after treatment of miR-297 mimic, whereas the opposite trends were observed in miR-297 inhibitor-treated HCC cells.