Previous studies have identified potential neurological influences of several WS genes, including DNAJC30, [19] FZD9, [20] GTF2I, [21–23] LIMK1 [13], and STX1A, [24] with a particularly compelling neurobiological mechanism involving myelin, brain structure, and social behavior identified in a GTF2I knockout mouse model [21]. This evidence concerns the gene LIMK1 and Werner syndrome.