On the other hand, the main reasons why we did not add MYCN status or chromosomes 11q aberration to classify ultra high-risk NB in this study can be summarized as follows: (1) Firstly, this study mainly aimed to develop a survival prediction nomogram that could be used for high-risk NB children in developing countries or regions that lack of necessary technical or financial resources to perform genomic analysis. This evidence concerns the gene MYCN and neuroblastoma.