,4,5 It is worth mentioning that several pathways (i.e., MYC target V1, Kras signaling up, androgen response, peroxisome, unfolded protein response) down-regulated by MRG-001 are also related to cancer and decreasing expression of these pathways such as MYC have been considered as novel therapeutic strategies for cancer treatment.35 This evidence concerns the gene KRAS and cancer.