VDR and Alzheimer disease: Several studies [11-16] and a recent meta-analysis [17] have described associations between AD and single-nucleotide polymorphisms (SNPs) in VDR, although most of these studies only evaluated the impact of the classical FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232), and TaqI (rs731236) VDR polymorphisms.