AFP and Cirrhosis: Similarly, in GSE14520, SART3 (low vs. high, HR 2.104, p = 0.001), main tumor size (>5 cm vs. ≤5 cm, HR 0.506, p = 0.002), cirrhosis (Yes vs. No, HR 0.231, p = 0.04), AFP (≥300 ng/ml vs. >300, HR 1.546, P = 0.049), TNM stage (I and II vs. III, HR 3.427, p < 0.001) and BCLC stage (stage 0 and A vs. B and C, HR 3.647, p < 0.001) were also significantly associated with poor prognosis (Figure 3C).