UBE2C and cancer: In addition, more UBE2C+ Epi‐C6 was distributed in the peripheral cancer region compared to the central cancer region, showing a higher oncogenic profile, demonstrating that UBE2C is the driver gene of LUAD metastasis.[74] Microsatellite nodules of hepatocellular carcinoma (HCC) are small cancerous foci that appear around the liver tissue of the primary tumor.