HCC diagnosis associated with older age, elevated liver enzymes (p ≤ 0.002 for ALT, AST, and GGT), higher iron indices (p ≤ 0.01 for sFe, sFerritin, and transferrin saturation), elevated liver inflammation scores at baseline (Table 2), and unsuccessful IFN treatment (p = 0.00001). The gene discussed is IFNA1; the disease is hepatocellular carcinoma.