After MTB is recognized, neutrophils quickly arrive at the site of infection, and then activate and secrete a large number of chemokines, including ILs, tumor necrosis factor alpha (TNF-α), monokine induced by IFN-inducible T cell alpha chemoattractant (I-TAC), macrophage inflammatory protein-1alpha (MIP-1α), monocyte chemoattractant protein (MCP), IFN-γ-inducible protein-10 (IP-10/CXCL10), and monokine induced by IFN-γ (MIG, CXCL9) [38,39,40]. Here, TNF is linked to infection.