The first standardized genetic toolkit for K. rhaeticus, isolated from kombucha tea pellicle, is developedAn N-acyl-homoserine lactone (AHL) enables spatial patterning, as shown through red fluorescence (RFP)An RNA-based silencing system repressing the UGPase-encoding gene (galU) stops BC production. The gene discussed is UGP2; the disease is breast cancer.