The in vivo localization of this dendrimer 1c-G5 after injection into the tumor of rats bearing intracerebral implants of F98 wild-type (F98WT) receptor (−) or EGFR gene-transfected F98EGFR glioma cells demonstrated a much larger localization in F98EGFR versus in F98WT gliomas [59]. This evidence concerns the gene EGFR and glioma.