TNFSF10 and central nervous system cancer: For example, a DNA-binding CPP peptide (YGRKKRRQRRR-G3-R9) composed of a cell-penetrating domain and a DNA-binding domain delivered the TRAIL-encoding gene into adipose tissue-derived mesenchymal stem cells (ASCs) to enhance expression of TRAIL and inhibit glioma cell proliferation in vitro and in vivo [141].