SMPD3 and psoriasis: In addition to the BLT4s discussed above, other factors important in the pathogenesis of psoriasis are being studied, including cytoplasmic phospholipase A2, glycerophosphodiester phosphodiesterase domain containing 3, arachidonate 12-lipoxygenase R type, phospholipase B-like 1, sphingomyelin phosphodiesterase 3, ganglioside GM2 activator, and serine palmitoyltransferase long chain subunit have been suggested as important gene targets to consider for future studies.