RENBP and Chagas disease: The results suggested that the mechanisms of four core herbs were mainly linked to pathways in cancer, the AGE-RAGE signaling pathway in diabetic complications, pancreatic cancer, small cell lung cancer, MicroRNAs in cancer, Endocrine resistance, Leishmaniasis, the IL-17 signaling pathway, HIF-1 signaling pathway, MAPK signaling pathway, Chagas disease, Acute myeloid leukemia, Thyroid hormone signaling pathway, and the NF-kappa B signaling pathway (Figure 14C–E).