SchA (isolated from Schisandra chinensis) was assessed in two 5-FU-resistant colon cancer cell lines (HCT116 and SW480); miR-195 expression was high in SchA-treated cells, which reduced cell viability through the inhibition of the PI3K/AKT and NF-κB pathways [105]. Here, AKT1 is linked to malignant colon neoplasm.