Previous studies have revealed that miR-155 and membrane-linked protein A2 (ANXA2) play a substantial role in CRC tissues/cells, not only modifying the miR-650/ANXA2 axis via the miR-155 pathway but also enhancing CRC progression and resistance to oxaliplatin via M2 macrophage polarization [109]. The gene discussed is ANXA2; the disease is colorectal carcinoma.