On the one hand, IGF2BP1 protects the degradation of PTEN mRNA and thus promotes the migration of tumor cells [98], while on the other hand, IGF2BP1 promotes the expression of C-Myc and MKI67 mRNA to regulate the proliferation and apoptosis of hepatocellular carcinoma cells [99]. The gene discussed is IGF2BP1; the disease is neoplasm.