MLC phosphorylation is regulated by the Rho associated coiled-coil containing protein kinases (ROCK, Rho kinase; subtypes ROCK1 and ROCK2) and myotonic dystrophy-related Cdc-42 binding kinases (MRCK; subtypes MRCKα and MRCKβ) [6,7,8]. The gene discussed is CDC42BPA; the disease is myotonic dystrophy.