Recently, serum biomarkers of inflammation (IL-6) and extracellular matrix components (N-terminal propeptide of type I procollagen (P1NP), Mac-2 binding protein glycosylation isomer (M2BPGi), type III procollagen (PIIINP) and hyaluronic acid) generated during fibrogenesis, were indicated as useful for determination the stages of NAFLD in children and adolescents [9,12]. This evidence concerns the gene IL6 and metabolic dysfunction-associated steatotic liver disease.