INS and Insulin resistance: Furthermore, the KD has been shown to lead to the reduction of hyperinsulinemia and the improvement of insulin sensitivity in patients with type 2 diabetes [56]; the improvement of patients suffering from non-alcoholic fatty liver disease (NAFLD) is instead determined by the reduction of insulin resistance due to the increased use of fatty acids in the ketogenesis process with consequent reduction of the synthesis of intrahepatic triglycerides (IHTG) [57].