We found a significant negative correlation between the IL-16 level and ASMI in females (Figure 1d, r = −0.342, p = 0.021) and identified elevated serum IL-16 as a risk factor for sarcopenia in females (OR: 9.53, 95% CI: 1.09, 83.44, p = 0.029). Here, IL16 is linked to sarcopenia.